Antibody-Drug Conjugates Are ‘Changing Outcomes’ in HR+ HER2– Breast Cancer
June 7th 2023Sara M. Tolaney, MD, MPH, discusses how, compared with antibody-drug conjugates, chemotherapy produces low response rates and disease control in the treatment of those with hormone receptor–positive, HER2-negative metastatic breast cancer.
HER2+ Metastatic Breast Cancer: Unmet Needs and Future Directions in Care
Closing out their review of the HER2+ metastatic breast cancer treatment landscape, expert oncologists look forward to future evolutions in the paradigm.
Managing HER2+ Breast Cancer With Leptomeningeal Metastases
Panelists center their discussion on the challenges inherent in managing leptomeningeal metastases in patients with HER2+ breast cancer.
Agents in Development for HER2+ Breast Cancer
Experts share brief insights on novel agents in development for HER2+ breast cancer and consider how they may impact the treatment landscape.
Optimizing Care of Patients on T-DXd for HER2+ mBC With CNS Disease
Centering discussion on trastuzumab deruxtecan use in HER2+ metastatic breast cancer, experts elucidate adverse event management and concurrent radiation therapy.
HER2+ Metastatic Breast Cancer: Guidance on MRI Use After CNS Radiation
A brief review on how best to use MRI following CNS-directed radiation therapy in patients with HER2+ metastatic breast cancer.
Patient Case 3: HER2+ Metastatic Breast Cancer With CNS Disease
Following review of the final patient scenario, panelists consider later-line treatment options in the setting of multiply relapsed HER2+ metastatic breast cancer.
Novel Combination Strategies in HER2+ Metastatic Breast Cancer With CNS Disease
Comprehensive review of novel combination treatment strategies being explored for patients with HER2+ breast cancer and brain metastases.