Non-Small Cell Lung Cancer (NSCLC)

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Latest News

Phase 3 CROWN trial findings suggest that patients with ALK-positive NSCLC may maintain efficacy even after reducing lorlatinib dosing to mitigate AEs.
Elucidating Lorlatinib Benefit, ALK TKI Sequencing in ALK-Positive NSCLC

April 14th 2025

Phase 3 CROWN trial findings suggest that patients with ALK-positive NSCLC may maintain efficacy even after reducing lorlatinib dosing to mitigate AEs.

Disease-free survival and minimal residual disease event-free status was maintained for most patients with adjuvant osimertinib for EGFR-mutant NSCLC.
Plasma-Based MRD Analysis May Predict Recurrence in EGFR-Mutant NSCLC

April 12th 2025

Patients with ALK-positive NSCLC not vulnerable to neurological adverse effects or prone to weight issues, might benefit from treatment with lorlatinib.
Considerations for TKI Selection and Sequencing in ALK-Positive NSCLC

April 7th 2025

Data from the phase 3 CheckMate 77T trial support the CHMP’s opinion on approving the perioperative nivolumab regimen for those with resectable NSCLC.
EU’s CHMP Recommends Approving Perioperative Nivolumab Combo in NSCLC

April 2nd 2025

The safety profiles of osimertinib monotherapy and combination therapy were consistent with prior reports in EGFR-mutated non–small cell lung cancer.
Osimertinib Shows Sustained Survival Benefit in EGFR-Mutant NSCLC

March 30th 2025