Study Shows Nivolumab-Chemo Combination Improves Survival in Gastric and Esophageal Cancers
August 11th 2020Bristol Myers Squibb announced that their phase 3 CheckMate-649 trial demonstrated superior overall survival and profession-free survival using nivolumab plus chemotherapy to treat patients with gastric and esophageal cancers.
Trial Evaluating Nivolumab for Patients with Esophageal Cancer Meets Primary End Point of DFS
August 11th 2020Bristol Myers Squibb’s CheckMate-577 trial, which evaluated nivolumab to treat patients with resected esophageal or gastroesophageal junction cancer, met the primary end point of disease-free survival.
Afatinib, Osimertinib Sequence Shows Promise for EGFR-Positive NSLC
August 10th 2020The GioTag study demonstrated that sequential afatinib and osimertinib improved overall survival among patients from the US with epidermal growth factor receptor mutation-positive non-small cell lung cancer and a T790M resistance mutation.
Nivolumab Plus Ipilimumab Improves OS in Malignant Pleural Mesothelioma
August 10th 2020Data from the phase 3 CheckMate-743 trial showed a statistically significant overall survival benefit for patients with previously untreated, unresectable malignant pleural mesothelioma when treated with nivolumab plus ipilimumab.
Breast Cancer Screening With MRI for Survivors of Childhood Cancer
August 7th 2020Jennifer M. Yeh, PhD, spoke about study findings which indicated that instituting annual breast cancer screening with MRI at ages 25 to 30 years may reduce breast cancer mortality by 50% or more in survivors of childhood cancer.
Phase 3 IMpassion131 Study Fails to Meet Primary End Point of PFS in Metastatic TNBC
August 7th 2020The study evaluating atezolizumab in combination with paclitaxel compared to placebo plus paclitaxel did not meet its primary end point of progression-free survival in patients with metastatic triple-negative breast cancer.
Risk of Second Cancer Diagnosis Following Various Radiation Therapy Modalities
August 5th 2020A recent study compared the risk of a second cancer diagnosis after primary cancer treatment following the use of either intensity-modulated radiotherapy, 3-dimensional conformal radiotherapy, or proton beam radiotherapy.
Unexpected Hospitalizations Result in Unfavorable Outcomes in Head and Neck Cancer
August 5th 2020A study conducted by the Roswell Park Comprehensive Cancer Center found that patients undergoing radiation therapy for head and neck cancers were at a higher risk of less-favorable outcomes if they were unexpectedly hospitalized for dehydration, fever, or other ailments.