Ide-cel or Standard Regimens in Relapsed and Refractory Multiple Myeloma
January 29th 2024Compare outcomes between ide-cel chimeric antigen receptor T-cell (CAR-T) therapy and standard treatment regimens such as pomalidomide and daratumumab combinations in patients with heavily pretreated relapsed and refractory multiple myeloma.
Collaborative Care and Access Challenges in Managing R/R MM with GPRC5D Bispecific
January 25th 2024Oncology Clinical Pharmacist Specialist Amir Ali delves into potential challenges related to access and the use of this therapy, providing a comprehensive perspective on the complexities of incorporating GPRC5-targeting bispecifics into R/R MM patient management.
Zanidatamab Combo Appears ‘Exciting’ in HER2+/HR+ Metastatic Breast Cancer
January 25th 2024High-grade adverse effects with zanidatamab plus palbociclib and fulvestrant seem to be uncommon in patients with HER2-positive, hormone receptor–positive, metastatic breast cancer, according to Sara Hurvitz, MD, FACP.
Multiple Myeloma: Evolving Therapies and Patient Well-Being
January 23rd 2024Noa Biran, MD, addresses unmet needs in relapsed/refractory multiple myeloma, focusing on reducing treatment burden and exploring fixed-duration therapies post-transplant, and highlights potential consolidation approaches with CAR-T cells or novel agents.
Sequencing Selinexor With Novel BCMA Therapies
January 23rd 2024Noa Biran, MD, discusses the potential sequencing of selinexor with newer B-cell maturation antigen (BCMA)-directed therapies like CAR-T cells and bispecific antibodies, and explores optimizing treatment sequences to maximize efficacy, minimize resistance, and manage toxicity profiles.
Approaches to Treatment and Staging in Unresectable NSCLC
January 23rd 2024Gregory Gan, MD, briefly outlines the available treatment strategies for stage III unresectable NSCLC, and Alykhan Nagji, MD explores the characterization of patients with unresectable stage III NSCLC, underscoring the crucial role of accurate staging in guiding treatment decisions.
Treatment Strategies for NSCLC Following Progression on Adjuvant Immunotherapy
January 23rd 2024Oncology experts from the University of Kansas discuss treatment strategies for both resectable and unresectable non-small cell lung cancer (NSCLC) following progression on adjuvant immunotherapy, providing valuable insights into navigating the challenges posed by this evolving clinical scenario.
Outcomes After Biochemical or Clinical Progression in Patients With Multiple Myeloma
January 22nd 2024Examine outcomes such as overall survival, progression-free survival, and response rates in multiple myeloma patients who have experienced biochemical or clinical progression after prior lines of therapy.
Navigating High-Risk Disease in Multiple Myeloma: Treatment Strategies and the Role of ASCT
January 19th 2024Experts dive into the complexities of defining and treating high-risk Multiple Myeloma (MM) and discuss the role of ASCT in newly diagnosed MM and weigh the considerations for recommending transplants, including insights on the selection criteria for tandem transplantations.