ONCOLOGY Vol 39, Issue 9

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This trial combines pembrolizumab and trabedersen to enhance treatment for advanced NSCLC, targeting TGF-β2 for improved patient outcomes.

Trabedersen (OT-101) With Pembrolizumab for Newly Diagnosed PD-L1–Positive Metastatic NSCLC

Omar K. Abughanimeh, MBBS;Anthony E. Maida III, PhD, MA, MBA;Sanjive Qazi, PhD;Kate-Lynn Muir, DO;Bhavina Sharma MD;Lynette Smith, PhD;Apar Kishor Ganti, MD

October 30th 2025

ArticleClinical Trials in Progress

Explore the promising role of antibody-drug conjugates targeting TROP2 in treating metastatic triple-negative breast cancer and improving patient outcomes.

3 Things You Should Know About Single-Agent ADCs in TNBC Treatment

ONCOLOGY Staff

October 29th 2025

ArticlePerspective

Explore the promising role of antibody-drug conjugates targeting TROP2 in treating metastatic triple-negative breast cancer and improving patient outcomes.

Granulosa cell tumors exhibit late recurrence and rare hepatic metastasis, emphasizing the need for lifelong surveillance in affected patients.

Late Hepatic Recurrence From Granulosa Cell Tumor: A Case Report

Prosper Akankwasa, MBBS;Jackson Kakooza, MBBS;Aisha Abdullahi Ahmed, MBBS;Catherine R. Lewis, MD, PhD

October 28th 2025

ArticleCase Study

Granulosa cell tumors exhibit late recurrence and rare hepatic metastasis, emphasizing the need for lifelong surveillance in affected patients.

Explore a rare case of vulvar epithelioid sarcoma, highlighting the role of SMARCB1 loss and the challenges of radiotherapy in treatment.

Unraveling the Complexities of Proximal-Type Epithelioid Sarcoma of the Vulva

Fatimah M. Kaabi, MBBS;Chaker Zaidi, MD, PhD;Fatimah Abdullah Alessa, MBBS;Yasser Sorour, MD, PhD

October 27th 2025

ArticleCase Study

PET-adapted strategies enhance treatment for advanced classical Hodgkin lymphoma, optimizing outcomes through individualized escalation and de-escalation based on PET results.

Progress in the Treatment of Advanced-Stage Classical Hodgkin Lymphoma in the PET-Adapted Era

Wael Abdulla Moh Khair, MD

October 26th 2025

ArticleCase Study

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions.

Convergent and Divergent Signaling Pathways in Cancer: A Dual-Axis Model for Adaptive Precision Oncology

Aliasgar Shahiwala, PhD

October 25th 2025

ArticleReview Article

Explore how oncogenes and signaling pathways converge and diverge in cancer, shaping diagnostic and therapeutic strategies for personalized interventions.